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KMID : 1137920120370040215
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Journal of Agricultral Medicine & Community Health
2012 Volume.37 No. 4 p.215 ~ p.222
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Association of Hemoglobin A1c with Visceral Fat Measured by Computed Tomography in Nondiabetic Adults
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Han A-Lum
Shin Sae-Ron
Park Seong-Hoon
Lee Jeong-Mi
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Abstract
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Objective: A prediabetes hemoglobin A1c (HbA1c) level of 5.7%?6.4% is considered a risk factor for diabetes mellitus and cardiovascular disease (CVD) in the USA. In this study, we assessed the HbA1c and visceral fat levels as CVD risk factors in health check-up examinees who were not yet diagnosed with diabetes.
Methods: Totally, 507 study subject were categorized as per criteria of the American Diabetes Association, depending on whether the HbA1c level was ≥5.7% or <5.7%. Lipid levels, blood pressure, BMI (kg/m2), total abdominal, and visceral fat levels were measured by computed tomography.
Results: The mean of HbA1c in the male group was larger than the mean in the female group and their values were, respectively, 6.03±0.82% and 5.88±0.72%(p<0.05). Only the mean values of age and visceral fat area were different between HbA1c≥5.7% and <5.7% in both male and female group(p<0.05). Visceral fat levels were significantly associated with HbA1c in the group of HbA1c ≥5.7% (odds ratio=1.005, 95% CI 1.002∼1.008).
Conclusions: Visceral fat levels were significantly higher and correlated with the group which HbA1c level is ≥5.7%. This finding suggests that subjects who have high levels of HbA1c should be carefully monitored during prediabetes and should have chance to have health education programs.
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KEYWORD
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Hemoglobin A1c, Visceral fat, Prediabete
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